Safety and Efficacy of TMS for Patients with Schizophrenia

Safety and Efficacy of TMS for Patients with Schizophrenia

Dr. Danish and Philadelphia Integrative Psychiatry now offer Transcranial Magnetic Stimulation (TMS) for a variety of mental health disorders, including depression, anxiety, OCD, PTSD, addiction, ADHD, and more. For our adult patients with ongoing depression, this treatment is covered by insurance. This blog will delve into some of the benefits and, most importantly, the favorable safety profile of TMS for patients with schizophrenia, focusing on both positive and negative symptoms.  

​​Effectiveness of TMS for Schizophrenia

Research on TMS for schizophrenia presents mixed results depending on the symptoms being treated. There is more evidence supporting the efficacy of TMS for negative symptoms of schizophrenia, but many studies also indicate its effectiveness and safety in treating positive symptoms. Importantly, the studies consistently support the safety of using TMS for patients with schizophrenia.

Addressing Negative Symptoms

Enhancement of Motivation and Emotional Expression

Negative symptoms like lack of motivation and emotional flatness can be particularly challenging to treat. TMS can target areas of the brain associated with motivation and emotional regulation, helping patients feel more engaged and expressive. Symptoms such as apathy and social withdrawal often do not respond well to medication. A review of 57 studies involving over 2,500 participants indicated that TMS might help alleviate these symptoms, leading to improved participation in social and occupational activities.

Boost in Cognitive Function

Cognitive deficits, such as difficulties with memory and attention, are common in schizophrenia. TMS has been found to enhance cognitive functions by stimulating the dorsolateral prefrontal cortex, which plays a crucial role in working memory and attention. This can help patients perform better in tasks that require concentration and memory recall.

Managing Positive Symptoms

Reduction in Hallucinations and Delusions

While the evidence is not as robust as it is for other disorders, there is a positive trend toward TMS improving positive symptoms in schizophrenia. This is significant because it shows that TMS, when done responsibly, has shown promise in safely reducing the severity and frequency of hallucinations and delusions, which are common positive symptoms of schizophrenia. 

Potential Cautions

Side Effects and Considerations

While TMS is generally well-tolerated, it is not without potential side effects. Some patients may experience mild headaches, scalp discomfort, or lightheadedness. It is crucial to conduct a thorough assessment to ensure that TMS is appropriate for each individual, particularly those with a history of seizures or other neurological conditions. Continuous monitoring and adjustments to the treatment protocol can help mitigate these risks.

Getting in Touch with Dr. Danish and his Team

At Philadelphia Integrative Psychiatry, we are excited to offer TMS as part of our repertoire of treatment options. We continue to stay on top of the latest research related to TMS so we can provide the best quality care in a safe manner. Our holistic and integrative approach ensures that we consider all aspects of our patients' well-being in developing personalized treatment plans. If you or a loved one are seeking support for schizophrenia or similar conditions, please text or call 610-999-6414 to learn how we can help.

For More Information on TMS

The following blogs by Dr. Danish focus on TMS for a variety of conditions and patient populations:

Sources:

  • ​​WebMD. (2023). Transcranial Magnetic Stimulation (TMS) for Schizophrenia. Retrieved from WebMD.

Hasan, A., et al. (2016). Efficacy of Transcranial Magnetic Stimulation for Negative Symptoms of Schizophrenia: A Systematic Review and Meta-Analysis. Schizophrenia Bulletin. Retrieved fromPubMed.

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The Safety of TMS in Treating Depression During Pregnancy