Understanding PANS: A Guide to Pediatric Acute-Onset Neuropsychiatric Syndrome

Introduction:

At Philadelphia Integrative Psychiatry, we view our patients as unique individuals, not just diagnoses. Our team, comprising mental health professionals and nutritionists with diverse backgrounds, is committed to providing personalized, holistic, and research-driven care. We focus on understanding both your physical health needs and mental health goals, offering integrative solutions that go beyond conventional approaches.

Our dedication to research and evidence-based practices guides us in the field of pediatric neuropsychiatric care. One significant piece of literature, "Clinical Management of Pediatric Acute-Onset Neuropsychiatric Syndrome: Part II—Use of Immunomodulatory Therapies" by Frankovich, MD, MS, et al., offers in-depth insights into the use of immunomodulatory therapies for children with acute-onset neuropsychiatric symptoms. This research, critical for healthcare professionals, highlights effective clinical strategies for managing pediatric neuropsychiatric disorders.

Pediatric Acute-onset Neuropsychiatric Syndrome (PANS) presents a complex challenge, with 75%80% of patients exhibiting immune abnormalities. The condition necessitates considering immunomodulatory therapies, especially for those with neuroinflammation or postinfectious autoimmunity. The PANS Research Consortium has developed treatment guidelines categorizing patients by disease severity and recommending tailored treatments ranging from watchful waiting to therapeutic plasma exchange for the most severe cases.

The guidelines provide a structured approach to treating PANS, emphasizing the need for individualized treatment plans. These recommendations highlight the importance of addressing the underlying immune dysfunctions in PANS through various therapies, including NSAIDs, corticosteroids, IVIG, and in severe cases, therapeutic plasma exchange or other immunomodulatory agents.

Philadelphia Integrative Psychiatry integrates these research findings into our practice, enhancing our ability to offer research-backed and holistic care to pediatric and young adult patients with PANS. Our approach ensures that treatment decisions are personalized, considering each patient's unique clinical presentation and response to therapy.

Your Journey to Wellness Begins with Philadelphia Integrative Psychiatry:

Your journey towards wellness and a PANS-free life starts with us. We are here to provide comprehensive and integrative care, supporting families and healthcare providers in the treatment of PANS. Visit our website www.phillyintegrative.com or contact us 610-999-6414 to learn more about how we can help you or your loved one on this path.

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