The Matthews Protocol has emerged as a significant advancement in the treatment of Disruptive Mood Dysregulation Disorder (DMDD) and other related mental health conditions. Dr. Danish has been utilizing the Matthews Protocol for years, adapting it with his own variations to achieve great success in patients who do not respond to the original approach.

Guanfacine and its extended-release formulation, Guanfacine ER (Intuniv), are medications primarily used in the treatment of attention deficit hyperactivity disorder (ADHD).