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Clonidine: A Surprising Ally in Psychiatry, Sleep, and Neuroinflammation

Clonidine is best known in psychiatry for its role in treating ADHD, especially in children and teens who struggle with impulsivity, hyperactivity, or emotional outbursts. As a non-stimulant option approved by the FDA, it’s often used when stimulant medications aren’t a good fit—or as an add-on to improve sleep, reduce reactivity, and calm the nervous system.

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