Pristiq (desvenlafaxine) is a medication primarily used to treat major depressive disorder (MDD) and is known for its effectiveness with potentially fewer sexual and weight side effects compared to other SNRIs and SSRIs.

Zoloft, known generically as sertraline, is a selective serotonin reuptake inhibitor SSRI commonly prescribed to treat a variety of mental health disorders. It works by increasing the amount of serotonin, a natural substance in the brain that helps with various mental health disorders.