Originally developed as an antidepressant, amitriptyline has been found to be effective for multiple disorders beyond depression, including anxiety disorders, chronic pain, and sleep disturbances. By increasing levels of serotonin and norepinephrine in the brain, amitriptyline helps regulate mood, alleviate pain, and improve sleep quality.

This research has a clear takeaway: women in their late 30s to 40s who are approaching menopause should be proactive about mental health. If you are entering perimenopause (or think you might be), it’s wise to be aware of the heightened risk for depression during this phase.

This article highlights the neurobiological underpinnings of menopausal depression, the limitations of conventional antidepressants, and the emerging evidence supporting hormonal interventions, particularly estrogen therapy.

Discover how behavioral activation and interpersonal connection through InterRhythmic Care significantly improve depression and anxiety symptoms while enhancing social functioning.

Explore how inflammatory biomarkers like IL-1β, IL-6, TNF-α, and CRP play a role in diagnosing and treating depression. Learn how Dr. Danish at Philadelphia Integrative Psychiatry integrates these insights into patient care.

A recent study has shown that psilocybin, the active ingredient in magic mushrooms, may be more effective than traditional antidepressants in treating depression.

Dr. Danish and his team frequently work with patients experiencing depression. Auvelity (AXS-05), a combination of dextromethorphan and bupropion, is primarily used for treating depression. This blog dives into the research behind Auvelity in patients with agitation related to Alzheimer’s research.

Dr. Danish frequently works with patients using various medications, including Bupropion, to manage a range of mental health conditions. Bupropion, also known as Wellbutrin, is a medication specifically designed to help individuals with depression, seasonal affective disorder (SAD), and smoking cessation.